The 401st Army Field Support Brigade headquartered at Bagram Airfield, Afghanistan, executes, directs and manages field and sustainment level logistics for both U.S. and selected Coalition Forces in Afghanistan. The brigade is part of the Army Sustainment Command which is headquartered at Rock Island Arsenal, Ill.

The 401st AFSB serves as the single entry point for integration and synchronization for acquisition, logistics and technology between the tactical level and the materiel enterprise while enhancing unit readiness and improving combat capability in accordance with ARCENT (U.S. Army Forces, U.S. Central Command) and USFOR-A (U.S. Forces-Army) priorities.